kengr: (Default)
[personal profile] kengr
.. or even "controlling".

http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2190741

Basically a woman who has been pregnant twice and delivered two healthy kids without medical intervention. And *she* is XY/XO. And one of her daughters is XY.

Tell me again about "XY = male, XX=female".

Date: 2009-08-21 12:08 am (UTC)
From: [identity profile] fayanora.livejournal.com
What is XO?

Date: 2009-08-21 01:06 am (UTC)
From: [identity profile] freetrav.livejournal.com
Basically, the sex-determination pair, normally XX or XY, isn't a pair, just a single X chromosome. The person who has this chromosomal abnormality will have a female phenotype.

The cases where a female phenotype turns out to be XY are generally cases of Androgen Insensitivity Syndrome, where the body doesn't respond to 'male' hormones such as testosterone, and thus manifests as female.

Date: 2009-08-21 03:52 am (UTC)
From: [identity profile] christinaathena.livejournal.com
This wasn't a case of AIS, though, as people with AIS have (often undescended) testes rather than ovaries, and no uterus. This is a very unusual case, since almost all XY females lack ovaries, and frequently lack a uterus as well. In fact, when I first read about XY females, years ago, it was said that it was XY females were invariably infertile. Obviously that's not completely true!

XO doesn't normally result in a typical female phenotype, however. XO females are generally infertile and usually have significant health problems, and lowered IQ. XO is embryonic lethal in something like 90-95% of cases, that is, 90-95% of XO zygotes will fail to reach full term.
Edited Date: 2009-08-21 03:57 am (UTC)

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